Bioinformatics- Assignment #4 (Week 4)

 Hello,

Today I explored the website interactome and STRING. While exploring these websites I searched up my assigned protein AMY1B and looked specifically at its different interactions. I first searched up AMY1B in interactomes database and in doing so, found that it interacted with the protein Mucin-7 or MUC7, which functions to promote the clearance of bacteria in the oral cavity. With that being said, I then searched up AMY1B on the website STRING, and it was here I found a series of different interactions with other proteins. Some of which were, H6PD, LCT, MGAM, and BPI just to name some. 

After, looking at the two websites I found that they both had very different results. For instance, interactome had only one interaction listed while STRING had a total of eight interactions! However, out of those eight interactions, only four were determined experimentally whereas the other remaining four were from curated databases. 

In closing, after exploring interactome and STRING I now know where I can go if I ever need more information on a protein. Specifically, what other proteins interact with the protein being investigated, and which in my case currently is AMY1B.

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